REGULATION OF T CELL DIFFERENTIATION AND FUNCTION BY EZH2

Regulation of T cell differentiation and function by EZH2

The enhancer of zeste homologue 2 (EZH2), one of the polycomb group (PcG) proteins, is the catalytic subunit of Polycomb-repressive complex 2 (PRC2) and induces the trimethylation of the histone H3 lysine 27 (H3K27me3) promoting epigenetic gene silencing.EZH2 contains kt196 torque converter a SET domain promoting the methyltransferase activity whil

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Dendritic Cells: a Spot on Sialic Acid

Glycans decorating cell surface and secreted proteins and lipids occupy the juncture where critical host-host and host-pathogen interactions occur.The role of lock shock and barrel art glycan epitopes in cell-cell and cell-pathogen adhesive events is already well-established, and cell surface glycan structures change rapidly in response to stimulus

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